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25.10.2021 12:16:44
Seminar: 6.01.16304_1d LFC1: IgE-Dependent and –Independent Histamine Release from Human Basophils - Details
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General information

Course name Seminar: 6.01.16304_1d LFC1: IgE-Dependent and –Independent Histamine Release from Human Basophils
Course number 6.01.16304_1d
Semester Sommersemester 2021
Current number of participants 3
maximum number of participants 7
Home institute Fakultät 6 Dekanat
Courses type Seminar in category Teaching
First date Tue., 20.04.2021 13:00 - 16:00, Room: (Synchron, BBB)
Lehrsprache deutsch

Course location / Course dates

(Synchron, BBB) Tuesday. 20.04.21, Tuesday. 27.04.21, Tuesday. 04.05.21, Tuesday. 18.05.21, Tuesday. 25.05.21, Tuesday. 01.06.21, Tuesday. 06.07.21, Tuesday. 13.07.21, Tuesday. 20.07.21, Tuesday. 27.07.21, Tuesday. 03.08.21, Tuesday. 10.08.21 13:00 - 16:00
Wednesday. 18.08.21 17:00 - 20:00
(Vertretung Gruppe Limberg (wegen Krankheit)) Thursday. 08.07.21 09:00 - 12:00


Basophils are granulocytes which are important sources of histamine and other pro-inflammatory mediators. Recent evidence suggests that basophils, despite their relative rarity compared to other immune cells, play a crucial immunomodulatory role in allergies and other diseases by supporting underlying Th2-type immune responses. The aims of this project are to assess the effects of either IgE-dependent (e.g. anti-IgE) or IgE-independent (e.g. fMLP) stimuli on the differential release of histamine from purified human basophils. These studies will involve learning the procedures for isolating basophils by Ficoll-density centrifugation and purification by immunomagnetic selection from human blood, as well as various experimental setups and determining histamine releases using spectrofluorometric autoanalysis. The project is expected to give students a comprehensive insight into immune cell isolation and studying allergic pro-inflammatory cell responses as well as basic skills in data analysis and literature reviews.

Lit. Falcone FH, Knol EF, Gibbs BF. The role of basophils in the pathogenesis of allergic disease. Clin Exp Allergy. 2011 Jul;41(7):939-47

Admission settings

The course is part of admission "SoSe 2021: Projektzuteilung LFC 1".
Liebe Studierende,

Am 01..04.2021 um 08:00 Uhr werden die Projekte für das LFC 1 freigeschaltet und Sie können sich selbstständig in die Projekte eintragen.
(Achtung: Wir können keine manuellen Eintragungen vornehmen. Bei Problemen wenden Sie sich bitte an den Stud.IP-Support!)

Sie müssen nicht sofort zu Beginn des Anmeldezeitraums vor dem PC sitzen – Vom 01.04.2021 bis zum 18.04.2021 um 23:59 Uhr können alle Studierenden gleichberechtigt auswählen! Sie können ggf. auch Ihre Auswahl noch nachträglich anpassen. Die Projekte LFC Jahr 1 werden am 19.04.2021 14:00 Uhr über ein automatisiertes Losverfahren zugeteilt.

Herzliche Grüße

Sabine Gronewold
Settings for unsubscribe:
  • Enrolment is allowed for up to 1 courses of the admission set.
  • The enrolment is possible from 01.04.2021, 08:00 to 23.04.2021, 23:59.
  • A defined number of seats will be assigned to these courses.
    The seats in the affected courses have been assigned at 19.04.2021 on 14:00. Additional seats may be available via a wait list.
  • The enrolment is only permitted for participants of the course: 6.01.16000a Ringvorlesung LFC1: Einführung in das wissenschaftliche Arbeiten (Sommersemester 2021) .
Assignment of courses: