Practical part:
In this module, the efficacy of environmental mimetics in a model system of multiple sclerosis will be investigated. Methodologically, a mouse model system of multiple sclerosis mixed, multicolor flow cytometry, various histological analyses, RNA extraction and quantitative real-time PCR will be used. The practical work will be performed mainly on primary mouse cells.

Theoretical part (seminar):
During the module the pathomechanisms of common CNS diseases (e.g., multiple sclerosis, Alzheimer's disease, Parkinson's disease) will be discussed in detail with a focus on the involvement of the immune system in the development as well as the progression of inflammatory and degenerative CNS diseases. At the same time, the relevance of environmental factors on these diseases will be discussed as well as the possibilities of environmental mimetic as therapeutic concepts.