Stud.IP Uni Oldenburg
Universität Oldenburg
30.11.2021 04:32:39
gsw060 - Epigenetics and Gene Regulation (Vollständige Modulbeschreibung)
Originalfassung Englisch PDF Download
Modulbezeichnung Epigenetics and Gene Regulation
Modulkürzel gsw060
Kreditpunkte 6.0 KP
Workload 180 h
Einrichtungsverzeichnis Department für Humanmedizin
Verwendbarkeit des Moduls
  • Master's Programme Molecular Biomedicine (Master) > Clinical Modules
Zuständige Personen
Plösch, Torsten (Modulverantwortung)
Heep, Axel (Modulverantwortung)
Plösch, Torsten (Prüfungsberechtigt)
Heep, Axel (Prüfungsberechtigt)
Hinz, Cornelia (Prüfungsberechtigt)
Teilnahmevoraussetzungen
Enrolment in Master´s programme Molecular Biomedicine
Kompetenzziele

Goals of the Module:
upon completion of this course, students
- know about epigenetic regulation of gene transcription
- can determine different epigenetic features
- have a basic understanding of the role of epigenetics in human disease

Competencies:
++ deepened biological expertise
  + deepened clinical expertise
++ deepened knowledge of biological working methods
  + deepened knowledge of clinical diagnostics
  + data analysis skills
  + critical and analytical thinking
  + ability to perform independent biological research
  + data presentation and discussion (written and spoken)
  +  teamwork

Modulinhalte

Lecture:
- introduction to epigenetics
- regulation of gene expression
- developmental epigenetics 
- cancer epigenetics
- current methods
- ethics

Seminar:
- presentation of important historical and current primary literature
- presentation and discussion of lab methods used in the practical part

Exercise:
- Designing bisulfite PCR strategies for methylated DNA
- analyses of datasets
- DNA isolation from cells
- in vitro methylation of DNA
- methylation-specific restriction analysis (and PCR)
- methylation-specific bisulfite PCR
- histone characterization

Literaturempfehlungen
Links
Unterrichtssprache Englisch
Dauer in Semestern 1 Semester
Angebotsrhythmus Modul summer term
Aufnahmekapazität Modul 12
Hinweise
The number of participants for this module is limited to 12. If there are more students registered than places available, lots will be drawn. Students which are enrolled in Master´s programme Molecular Biomedicine will be preferred.
Modullevel / module level MM (Mastermodul / Master module)
Modulart / typ of module Wahlpflicht / Elective
Lehr-/Lernform / Teaching/Learning method
Vorkenntnisse / Previous knowledge basic knowledge in cell and developmental biology, solid knowledge in genetics
Lehrveranstaltungsform Kommentar SWS Angebotsrhythmus Workload Präsenz
Vorlesung
1 SoSe 14
Seminar
1 SoSe 14
Übung
2 SoSe 28
Präsenzzeit Modul insgesamt 56 h
Prüfung Prüfungszeiten Prüfungsform
Gesamtmodul

presentation 50%

protocol 50%