gsw070 - Gene-based Therapies in Human diseases (Vollständige Modulbeschreibung)

gsw070 - Gene-based Therapies in Human diseases (Vollständige Modulbeschreibung)

Originalfassung Englisch PDF Download
Modulbezeichnung Gene-based Therapies in Human diseases
Modulkürzel gsw070
Kreditpunkte 6.0 KP
Workload 180 h
Einrichtungsverzeichnis Department für Humanmedizin
Verwendbarkeit des Moduls
  • Master's Programme Molecular Biomedicine (Master) > Clinical Modules
Zuständige Personen
  • Neidhardt, John (Modulverantwortung)
  • Neidhardt, John (Prüfungsberechtigt)
  • Jüschke, Christoph (Prüfungsberechtigt)
Teilnahmevoraussetzungen
Enrolment in Master´s programme Molecular Biomedicine
Kompetenzziele
Competencies:
++ deepened biological expertise
++ deepened clinical expertise
++ deepened knowledge of biological working methods
  + deepened knowledge of clinical diagnostics
  + data analysis skills
  + interdisciplinary thinking
++ critical and analytical thinking
  + independent searching and knowledge of scientific literature
++ ability to perform independent biological research
  + data presentation and discussion (written and spoken)
  + team work
  + project and time management

Adressing students with emphasis on translational/therapeutical interest in molecular biology, molecular genetics, cell biology and neurobiology.
Modulinhalte
The module focuses on translational research in human genetics, molecular biology, molecular genetics, translational medicine, cell- and neurobiology.

Subjects of the lecture: Therapeutic strategies and research applications, molecular bases of neurodegenerative diseases, structure and function of DNA/RNA/proteins/membranes.

Lecture: To improve knowledge in molecular genetics, molecular biology and cell biology in correlation with human diseases, gain knowledge in Antisense-Oligonucleotide-, U1- and CRISPR-based genetic therapies, viruses in gene therapy, cell sorting and diagnosis by FACS.

Exercises: Learning current methods of therapy development; molecular biology and human genetics; high throughput technologies; introduction to cell cultivation techniques.

Learn to transfer the theoretical knowledge to experiments. Gaining methodological knowledge in molecular genetics, cell biology and therapeutic approaches. Initial training on how to perform research projects.
Literaturempfehlungen
Molecular Biology of the Cell (Alberts et al., 6th edition)
Links
Unterrichtssprache Englisch
Dauer in Semestern 1 Semester
Angebotsrhythmus Modul summer semester
Aufnahmekapazität Modul 15
Modulart Wahlpflicht / Elective
Modullevel MM (Mastermodul / Master module)
Lehr-/Lernform Lecture and Exercise
Vorkenntnisse basic knowledge of cell biology, genetics
Lehrveranstaltungsform Kommentar SWS Angebotsrhythmus Workload Präsenz
Vorlesung 1 SoSe 14
Übung 3 SoSe 42
Präsenzzeit Modul insgesamt 56 h
Prüfung Prüfungszeiten Prüfungsform
Gesamtmodul
50% presentation or written examination or oral examination,
50% protocols