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gsw070 - Gene-based Therapies in Human diseases (Complete module description)
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Module label Gene-based Therapies in Human diseases
Module abbreviation gsw070
Credit points 6.0 KP
Workload 180 h
Institute directory Department of Human Medicine
Applicability of the module
  • Master's Programme Molecular Biomedicine (Master) > Clinical Modules
Responsible persons
  • Neidhardt, John (module responsibility)
  • Neidhardt, John (authorised to take exams)
  • Jüschke, Christoph (authorised to take exams)
Prerequisites
Enrolment in Master´s programme Molecular Biomedicine
Skills to be acquired in this module
Competencies:
++ deepened biological expertise
++ deepened clinical expertise
++ deepened knowledge of biological working methods
  + deepened knowledge of clinical diagnostics
  + data analysis skills
  + interdisciplinary thinking
++ critical and analytical thinking
  + independent searching and knowledge of scientific literature
++ ability to perform independent biological research
  + data presentation and discussion (written and spoken)
  + team work
  + project and time management

Adressing students with emphasis on translational/therapeutical interest in molecular biology, molecular genetics, cell biology and neurobiology.
Module contents
The module focuses on translational research in human genetics, molecular biology, molecular genetics, translational medicine, cell- and neurobiology.

Subjects of the lecture: Therapeutic strategies and research applications, molecular bases of neurodegenerative diseases, structure and function of DNA/RNA/proteins/membranes.

Lecture: To improve knowledge in molecular genetics, molecular biology and cell biology in correlation with human diseases, gain knowledge in Antisense-Oligonucleotide-, U1- and CRISPR-based genetic therapies, viruses in gene therapy, cell sorting and diagnosis by FACS.

Exercises: Learning current methods of therapy development; molecular biology and human genetics; high throughput technologies; introduction to cell cultivation techniques.

Learn to transfer the theoretical knowledge to experiments. Gaining methodological knowledge in molecular genetics, cell biology and therapeutic approaches. Initial training on how to perform research projects.
Recommended reading
Molecular Biology of the Cell (Alberts et al., 6th edition)
Links
Language of instruction English
Duration (semesters) 1 Semester
Module frequency summer semester
Module capacity 15
Type of module Wahlpflicht / Elective
Module level MM (Mastermodul / Master module)
Teaching/Learning method Lecture and Exercise
Previous knowledge basic knowledge of cell biology, genetics
Type of course Comment SWS Frequency Workload of compulsory attendance
Lecture 1 SoSe 14
Exercises 3 SoSe 42
Total module attendance time 56 h
Examination Examination times Type of examination
Final exam of module
written examination (90 min.)
additionally ungraded: signed lab protocols and regular active participation is required for the module to be passed