|Module label||Gene-based Therapies in Human diseases|
|Credit points||6.0 KP|
|Institute directory||Department of Human Medicine|
|Applicability of the module||
Enrolment in Master´s programme Molecular Biomedicine
|Skills to be acquired in this module||
++ deepened biological expertise
++ deepened clinical expertise
++ deepened knowledge of biological working methods
+ deepened knowledge of clinical diagnostics
+ data analysis skills
+ interdisciplinary thinking
++ critical and analytical thinking
+ independent searching and knowledge of scientific literature
++ ability to perform independent biological research
+ data presentation and discussion (written and spoken)
+ team work
+ project and time management
Adressing students with emphasis on translational/therapeutical interest in molecular biology, molecular genetics, cell biology and neurobiology.
The module focuses on translational research in human genetics, molecular biology, molecular genetics, translational medicine, cell- and neurobiology.
Subjects of the lecture: Therapeutic strategies and research applications, molecular bases of neurodegenerative diseases, structure and function of DNA/RNA/proteins/membranes.
Lecture: To improve knowledge in molecular genetics, molecular biology and cell biology in correlation with human diseases, gain knowledge in Antisense-Oligonucleotide-, U1- and CRISPR-based genetic therapies, viruses in gene therapy, cell sorting and diagnosis by FACS.
Exercises: Learning current methods of therapy development; molecular biology and human genetics; high throughput technologies; introduction to cell cultivation techniques.
Learn to transfer the theoretical knowledge to experiments. Gaining methodological knowledge in molecular genetics, cell biology and therapeutic approaches. Initial training on how to perform research projects.
Molecular Biology of the Cell (Alberts et al., 6th edition)
|Language of instruction||English|
|Duration (semesters)||1 Semester|
|Module frequency||summer semester|
|Module level||MM (Mastermodul / Master module)|
|Type of module||Wahlpflicht / Elective|
|Teaching/Learning method||Lecture and Exercise|
|Previous knowledge||basic knowledge of cell biology, genetics|
|Type of course||Comment||SWS||Frequency||Workload of compulsory attendance|
|Total module attendance time||56 h|
|Examination||Examination times||Type of examination|
|Final exam of module||
written examination (90 min.)
additionally ungraded: signed lab protocols and regular active participation is required for the module to be passed