gsw070 - Gene-based Therapies in Human diseases (Vollständige Modulbeschreibung)

Enrolment in Master´s programme Molecular Biomedicine

Competencies:
++ deepened biological expertise
++ deepened clinical expertise
++ deepened knowledge of biological working methods
  + deepened knowledge of clinical diagnostics
  + data analysis skills
  + interdisciplinary thinking
++ critical and analytical thinking
  + independent searching and knowledge of scientific literature
++ ability to perform independent biological research
  + data presentation and discussion (written and spoken)
  + team work
  + project and time management

Adressing students with emphasis on translational/therapeutical interest in molecular biology, molecular genetics, cell biology and neurobiology.

The module focuses on translational research in human genetics, molecular biology, molecular genetics, translational medicine, cell- and neurobiology.

Subjects of the lecture: Therapeutic strategies and research applications, molecular bases of neurodegenerative diseases, structure and function of DNA/RNA/proteins/membranes.

Lecture: To improve knowledge in molecular genetics, molecular biology and cell biology in correlation with human diseases, gain knowledge in Antisense-Oligonucleotide-, U1- and CRISPR-based genetic therapies, viruses in gene therapy, cell sorting and diagnosis by FACS.

Exercises: Learning current methods of therapy development; molecular biology and human genetics; high throughput technologies; introduction to cell cultivation techniques.

Learn to transfer the theoretical knowledge to experiments. Gaining methodological knowledge in molecular genetics, cell biology and therapeutic approaches. Initial training on how to perform research projects.

Molecular Biology of the Cell (Alberts et al., 6th edition)

https://uol.de/humangenetik/research-and-clinical-collaborations/

50% presentation or written examination or oral examination,
50% protocols