neu190 - Biochemical concepts in signal transduction (Veranstaltungsübersicht)

Course in the second half of the semester

within 2 months after the end of the course

50% written exam of 90 min., 50% report(s)
Paper(s) are to be read.
Regular active participation is required for the module to be passed.

Neurosci. knowlg. Expt. methods Independent research + Scient. literature + Social skills
++ Interdiscipl. knowlg. Maths/Stats/Progr. + Data present./disc. + Scientific English Ethics
Upon successful completion of this course, students

• know fundamental principles of molecular mechanisms of signal processing in cells
• know the properties and functional roles of proteins involved in signaling pathways
• have a basic understanding of structure-function relationships of receptor molecules (e.g. G-protein-coupled receptors) and their down-stream targets
• know the main hypotheses and their experimental confirmation in selected signal transduction pathways
• are able to discuss and present current concepts and knowledge of cellular signaling
• learn by selected experiments, how to study experimentally protein function in signaling
• are able to assess experimentally prepared data sets and have a good command of how to present them scientifically
• have a basic knowledge how to plan and perform a sequential set of experiments in molecular life sciences
• have a basic knowledge how to operate and use scientific equipment like spectrophotometer, fluorescence spectrophotometer, clean benches in cell culture and chromatographic systems

(HPLC)