gsw150 Research Project Molecular Biomedicine (Veranstaltungsübersicht)

Department für Humanmedizin

15 KP

all teachers of the curriculum (module counselling, authorized examiners)

Modulteile

Semesterveranstaltungen Wintersemester 2024/2025

Prüfungsleistung

Seminar

6.04.150.002 - Ophthalmology – Molecular and cellular mechanisms in regenerative Medicine
- Priv.-Doz. Dr. Sonja Mertsch
Please contact the lecturer for further information.
6.04.150.017 - Molekulare und zelluläre Mechanismen neuronaler Differenzierung
- Prof. Dr. Anja Bräuer
6.04.150.013 - Effects of aryl hydrocarbon receptor (AhR) antagonists on bone marrow derived dendritic cells (bmDC)
- Dr. Mai Ngoc Hoang
- Prof. Dr. Karin Loser
Seminar: - Presentation and discussion of laboratory methods used in the practical part - Basic knowledge in immunology and immune cell subsets - Role of aryl hydrocarbon receptor signaling in immunology and immune therapy - Role of dendritic cells during antigen presentation and bridging innate and adaptive immunity Exercise: This module involves working on small research projects. The projects include basic immunology with the goal to better understand the phenotype and function of dendritic cells as well as possibilities to modulate their maturation, activation and antigen presenting capacity.
6.03.617 - Human Genetics - Transcriptome and Exome analyses in neuronal and neurosensory diseases
- Christoph Jüschke
- Prof. Dr. John Neidhardt
6.04.150.019 - GLUT-Receptor Expression in different Mice strains
- Dr. rer. nat. Ulrike Meyer
- Prof. Dr. med. Bernhard Rauch
6.04.150.001 - Gynaecology and Obstetrics – Immunological and cellular mechanisms of gynaecological disorders
- Dr. Lena Dübbel
Please contact Dr. Lena Dübbel for individual timing and information (during office hours or by e-mail).
6.03.662 - Neurogenetics - Analysis of mouse models for deafness
- Dr. Maike Claußen
6.04.150.004 - Measurement of olfactory gene expression in adult and neonatal nasal swab samples
- Dr. rer. nat. Cornelia Hinz
Please contact Dr. Janina Noster for individual timing and information (during office hours or by e-mail).
6.03.614 - Human Genetics - Developing therapies to treat splice defect
- Christoph Jüschke
6.04.150.008 - Measurement of olfactory gene expression in adult and neonatal nasal swab samples
- Dr. rer. nat. Cornelia Hinz
Please contact Dr. Janina Noster for individual timing and information (during office hours or by e-mail).
6.04.150.012 - Immunological and cellular mechanisms of obstetrical disorders
- Dr. rer. nat. Anna Göken-Riebisch
Please contact Dr. Göken-Riebisch for individual timing and information (during office hours or by e-mail).
6.03.630 - Project: Biochemistry - Protein function in neurosensory systems
- Prof. Dr. Karl-Wilhelm Koch, Dipl.-Chem.
Termin nach Vereinbarung. Dieses Modul wird in den Räumen der Abt. Biochemie durchgeführt. Anmeldung bei Prof. Koch in der Sprechstunde.
6.03.615 - Human Genetics - Mutation identification, pathogenic mechanisms and therapy development
- Prof. Dr. John Neidhardt
6.03.670 - Visual Neuroscience - Computational analysis of retinal population responses
- Dr. rer. nat. Malte Ahlers
- Prof. Dr. Martin Greschner
6.04.150.023 - Epigenetic Regulation of AHR by zebularine in a rat cell line
- Prof. Dr. Torsten Plösch, Ph.D.
Please contact Dr. Janina Noster for individual timing and information (during office hours or by e-mail).
6.04.150.021 - Molecular Virology – virus host interactions
- Dr. rer. nat. Volker Kinast
6.04.150.016 - Macrophage polarisation in pancreatic adenocarcinoma
- Dr. rer. nat. Helge Meyer
6.03.671 - Visual Neuroscience - Visual Neuroscience - Retinal physiology
- Dr. rer. nat. Malte Ahlers
- Prof. Dr. Martin Greschner
6.04.150.005 - Novel immunomodulatory tripeptides for the in vitro treatment of murine immune and endothelial cells
- Prof. Dr. Karin Loser
- Dr. rer. nat. Nadine Mykicki
KdPT is a tripeptide structurally related to the C-terminal amino acids of alpha-melanocyte-stimulating hormone, which was previously shown to exhibit anti-inflammatory effects in various inflammatory diseases. However, due to its unfavourable physical and chemical properties KdPT is for instance not suitable for topical application. Hence, KdPT was modiﬁed to improve its physical and chemical properties. To analyze the effect of the KdPT derivatives, phenotype, function and migratory activity will be analyzed in primary mouse immune cells by multicolor flow cytometry, multiplex bead assays or quantitative PCRs. Furthermore, the effect of the anti-inflammatory tripeptide on mouse endothelial cells will be analyzed by performing immunofluorescence staining and (if time is available) and transendothelial electrical resistance (TEER) assays.
6.03.616 - Human Genetics - Severe diseases of the cilium: signal transduction and treatment options
- Christoph Jüschke
- Prof. Dr. John Neidhardt
6.03.661 - Neurogenetics - Evolution of the auditory system
- Dr. Maike Claußen
6.04.150.010 - Neurosurgery - Basic research in stroke
- Dr. Patrick Dömer
- Dr. rer. nat. Simeon Helgers
Please contact Dr. Simeon Helgers for individual timing and information.
6.04.150.015 - Physiologie Department Humanmedizin
- Prof. Dr. Ivan Milenkovic
6.04.150.006 - Perioperative Inflammation & Infection: Basic research in cardiovascular diseases - Heartfailure
- Prof. Dr. Gregor Theilmeier
6.04.150.003 - Novel immunomodulatory tripeptides for the in vitro treatment of human immune and endothelial cells
- Dr. rer. nat. Nadine Mykicki
KdPT is a tripeptide structurally related to the C-terminal amino acids of alpha-melanocyte-stimulating hormone, which was previously shown to exhibit anti-inflammatory effects in various inflammatory diseases. However, due to its unfavorable physical and chemical properties KdPT is for instance not suitable for topical application. Hence, KdPT was modiﬁed to improve its physical and chemical properties. To analyze the effect of the KdPT derivatives, phenotype and function will be analyzed in human immune cells by multicolor flow cytometry, multiplex bead assays or quantitative PCR. Furthermore, the effect of the anti-inflammatory tripeptide on human endothelial cells will be analyzed by performing immunofluorescence staining and (if time is available) and transendothelial electrical resistance (TEER) assays.
6.03.676 - RM_Visual Neuroscience - Molecular and cellular basis of regeneration in the peripheral nervous system
- Dr. Patrick Dömer
6.04.150.007 - Perioperative Inflammation & Infection: Basic research in cardiovascular diseases - Coronary artery disease
- Prof. Dr. Gregor Theilmeier
6.04.150.024 - Using zidovudine to combat drug-resistant bacteria
- Timo Jakob Benjamin van Eldijk
6.04.150.014 - Ophthalmology – Nerve regeneration in the ocular surface
- Priv.-Doz. Dr. Sonja Mertsch
Please contact the lecturer for further information.
6.03.660 - Neurogenetics - Structure-function analyses of the potassium chloride cotransporter KCC2
- PD Dr. Anna-Maria Hartmann
hier können Praxismodule (BA) und Research Module (MA), sowie BA und MA Arbeiten bei mir belegt werden.
6.03.680 - Neurosensorics - Vertebrate retina: Immunohistochemistry, intracellular dye injections, microscopy and image analysis
- Prof. Dr. Karin Dedek
joint pre-meeting with all other research modules (one week before the semester starts)
6.03.685 - Anatomy - Molecular and cellular mechanisms of neuronal differentiation
- Dr. rer. nat. Nicola Brandt
- Prof. Dr. Anja Bräuer
6.04.150.022 - Molekulare und zelluläre Mechanismen neuronaler Differenzierung
- Prof. Dr. Anja Bräuer

Projekt Individuelles Forschungsprojekt

6.04.150.002 - Ophthalmology – Molecular and cellular mechanisms in regenerative Medicine
- Priv.-Doz. Dr. Sonja Mertsch
Please contact the lecturer for further information.
6.04.150.017 - Molekulare und zelluläre Mechanismen neuronaler Differenzierung
- Prof. Dr. Anja Bräuer
6.04.150.013 - Effects of aryl hydrocarbon receptor (AhR) antagonists on bone marrow derived dendritic cells (bmDC)
- Dr. Mai Ngoc Hoang
- Prof. Dr. Karin Loser
Seminar: - Presentation and discussion of laboratory methods used in the practical part - Basic knowledge in immunology and immune cell subsets - Role of aryl hydrocarbon receptor signaling in immunology and immune therapy - Role of dendritic cells during antigen presentation and bridging innate and adaptive immunity Exercise: This module involves working on small research projects. The projects include basic immunology with the goal to better understand the phenotype and function of dendritic cells as well as possibilities to modulate their maturation, activation and antigen presenting capacity.
6.03.617 - Human Genetics - Transcriptome and Exome analyses in neuronal and neurosensory diseases
- Christoph Jüschke
- Prof. Dr. John Neidhardt
6.04.150.019 - GLUT-Receptor Expression in different Mice strains
- Dr. rer. nat. Ulrike Meyer
- Prof. Dr. med. Bernhard Rauch
6.04.150.001 - Gynaecology and Obstetrics – Immunological and cellular mechanisms of gynaecological disorders
- Dr. Lena Dübbel
Please contact Dr. Lena Dübbel for individual timing and information (during office hours or by e-mail).
6.03.662 - Neurogenetics - Analysis of mouse models for deafness
- Dr. Maike Claußen
6.04.150.004 - Measurement of olfactory gene expression in adult and neonatal nasal swab samples
- Dr. rer. nat. Cornelia Hinz
Please contact Dr. Janina Noster for individual timing and information (during office hours or by e-mail).
6.03.614 - Human Genetics - Developing therapies to treat splice defect
- Christoph Jüschke
6.04.150.008 - Measurement of olfactory gene expression in adult and neonatal nasal swab samples
- Dr. rer. nat. Cornelia Hinz
Please contact Dr. Janina Noster for individual timing and information (during office hours or by e-mail).
6.04.150.012 - Immunological and cellular mechanisms of obstetrical disorders
- Dr. rer. nat. Anna Göken-Riebisch
Please contact Dr. Göken-Riebisch for individual timing and information (during office hours or by e-mail).
6.03.630 - Project: Biochemistry - Protein function in neurosensory systems
- Prof. Dr. Karl-Wilhelm Koch, Dipl.-Chem.
Termin nach Vereinbarung. Dieses Modul wird in den Räumen der Abt. Biochemie durchgeführt. Anmeldung bei Prof. Koch in der Sprechstunde.
6.03.615 - Human Genetics - Mutation identification, pathogenic mechanisms and therapy development
- Prof. Dr. John Neidhardt
6.03.670 - Visual Neuroscience - Computational analysis of retinal population responses
- Dr. rer. nat. Malte Ahlers
- Prof. Dr. Martin Greschner
6.04.150.023 - Epigenetic Regulation of AHR by zebularine in a rat cell line
- Prof. Dr. Torsten Plösch, Ph.D.
Please contact Dr. Janina Noster for individual timing and information (during office hours or by e-mail).
6.04.150.021 - Molecular Virology – virus host interactions
- Dr. rer. nat. Volker Kinast
6.03.671 - Visual Neuroscience - Visual Neuroscience - Retinal physiology
- Dr. rer. nat. Malte Ahlers
- Prof. Dr. Martin Greschner
6.04.150.005 - Novel immunomodulatory tripeptides for the in vitro treatment of murine immune and endothelial cells
- Prof. Dr. Karin Loser
- Dr. rer. nat. Nadine Mykicki
KdPT is a tripeptide structurally related to the C-terminal amino acids of alpha-melanocyte-stimulating hormone, which was previously shown to exhibit anti-inflammatory effects in various inflammatory diseases. However, due to its unfavourable physical and chemical properties KdPT is for instance not suitable for topical application. Hence, KdPT was modiﬁed to improve its physical and chemical properties. To analyze the effect of the KdPT derivatives, phenotype, function and migratory activity will be analyzed in primary mouse immune cells by multicolor flow cytometry, multiplex bead assays or quantitative PCRs. Furthermore, the effect of the anti-inflammatory tripeptide on mouse endothelial cells will be analyzed by performing immunofluorescence staining and (if time is available) and transendothelial electrical resistance (TEER) assays.
6.03.616 - Human Genetics - Severe diseases of the cilium: signal transduction and treatment options
- Christoph Jüschke
- Prof. Dr. John Neidhardt
6.03.661 - Neurogenetics - Evolution of the auditory system
- Dr. Maike Claußen
6.04.150.010 - Neurosurgery - Basic research in stroke
- Dr. Patrick Dömer
- Dr. rer. nat. Simeon Helgers
Please contact Dr. Simeon Helgers for individual timing and information.
6.04.150.015 - Physiologie Department Humanmedizin
- Prof. Dr. Ivan Milenkovic
6.04.150.006 - Perioperative Inflammation & Infection: Basic research in cardiovascular diseases - Heartfailure
- Prof. Dr. Gregor Theilmeier
6.04.150.003 - Novel immunomodulatory tripeptides for the in vitro treatment of human immune and endothelial cells
- Dr. rer. nat. Nadine Mykicki
KdPT is a tripeptide structurally related to the C-terminal amino acids of alpha-melanocyte-stimulating hormone, which was previously shown to exhibit anti-inflammatory effects in various inflammatory diseases. However, due to its unfavorable physical and chemical properties KdPT is for instance not suitable for topical application. Hence, KdPT was modiﬁed to improve its physical and chemical properties. To analyze the effect of the KdPT derivatives, phenotype and function will be analyzed in human immune cells by multicolor flow cytometry, multiplex bead assays or quantitative PCR. Furthermore, the effect of the anti-inflammatory tripeptide on human endothelial cells will be analyzed by performing immunofluorescence staining and (if time is available) and transendothelial electrical resistance (TEER) assays.
6.03.676 - RM_Visual Neuroscience - Molecular and cellular basis of regeneration in the peripheral nervous system
- Dr. Patrick Dömer
6.04.150.007 - Perioperative Inflammation & Infection: Basic research in cardiovascular diseases - Coronary artery disease
- Prof. Dr. Gregor Theilmeier
6.04.150.024 - Using zidovudine to combat drug-resistant bacteria
- Timo Jakob Benjamin van Eldijk
6.04.150.014 - Ophthalmology – Nerve regeneration in the ocular surface
- Priv.-Doz. Dr. Sonja Mertsch
Please contact the lecturer for further information.
6.03.660 - Neurogenetics - Structure-function analyses of the potassium chloride cotransporter KCC2
- PD Dr. Anna-Maria Hartmann
hier können Praxismodule (BA) und Research Module (MA), sowie BA und MA Arbeiten bei mir belegt werden.
6.03.680 - Neurosensorics - Vertebrate retina: Immunohistochemistry, intracellular dye injections, microscopy and image analysis
- Prof. Dr. Karin Dedek
joint pre-meeting with all other research modules (one week before the semester starts)
6.03.685 - Anatomy - Molecular and cellular mechanisms of neuronal differentiation
- Dr. rer. nat. Nicola Brandt
- Prof. Dr. Anja Bräuer
6.04.150.022 - Molekulare und zelluläre Mechanismen neuronaler Differenzierung
- Prof. Dr. Anja Bräuer

Hinweise zum Modul

Teilnahmevoraussetzungen	as defined in the admission and examination regulations
Prüfungsleistung Modul	graded: project report ↵ungraded: participation in seminar and 30 min. presentation
Kompetenzziele	Competencies: ++ deepened biological and / or clinical expertise ++ deepened knowledge of biological working methods and / or clinical diagnostics ++ data analysis skills + interdisciplinary thinking ++ critical and analytical thinking ++ independent searching and knowledge of scientific literature ++ ability to perform independent biological research ++ data presentation and discussion (written and spoken) + team work + ethics and professional behaviour + project and time management