Clinical genetics is the medical specialty responsible for diagnosing genetic conditions and counselling individuals and their relatives who may be affected. All professionals involved agree on the primary goal of genetic counselling, which is to improve patient empowerment. Currently, counselling practices in Germany are not standardized, and vary in content and procedure compared to other European countries. The content and process of counselling sessions currently depend solely on the patient group (e.g. oncology or perinatal) and the reason for referral. However, they are not personalized according to patients’ needs or their prior levels of empowerment. Personalization according to patients' needs would optimize the efficacy and efficiency of genetic diagnostics and counselling, which is also a European goal (McAllister et al., 2016). Nevertheless, much remains to be understood about the development of patient empowerment before this goal can be achieved for diverse counselee populations. Therefore, there is an urgent need for the systematic monitoring of genetic counselling processes in Germany. However, no psychometrically evaluated tools exist for this purpose that take patients’ genetic literacy into account. The proposed project will evaluate a set of instruments for use in genetic counselling settings to monitor processes and outcomes among diverse counselee populations. Data collection is currently ongoing, and evaluation can begin at any time.