Stud.IP Uni Oldenburg
University of Oldenburg
06.12.2021 16:32:41
Veranstaltungsverzeichnis

Department of Human Medicine Click here for PDF-Download

Winter semester 2021/2022 13 Seminars
VAK Course Number Title Type Lecture
Preliminary studies
Advanced courses
Practical course
Colloquium
Research group
Workgroup
Project group
Council conference
Internship
Language course
Subject didactics
Excursion
Tutorial
Committee
SWS Semester weekly hours Teachers Degree
6.04.132 Regenerative Medicine in Ophthalmology Dates on Thursday. 14.10.21 09:00 - 10:00, Monday. 14.02.22 - Friday. 18.02.22, Monday. 21.02.22 - Friday. 25.02.22 12:00 - 17:00
Description:
Exercises - Dr. rer. nat. Sonja Mertsch
  • Master
6.04.150.004 Immunology - Anti-inflammatory drugs from bacteria and their potential application in the treatment of psoriasis The course times are not decided yet.
Description:
Practical part: During infection, bacteria, such as Yersinia enterocolitica, can actively translocate anti-inflammatory proteins into the host cell cytoplasm to suppress the host immune response. These proteins can be produced recombinantly and are to be formulated as drugs for therapy. For this purpose, the mouse model of imiquimod-induced psoriasis-like skin inflammation was used, and the animals were treated with the bacterial compounds. After the efficacy has been proven based on the reduction in disease severity, the mechanism of action shall be analyzed in detail. For this purpose, the induction of apoptosis, the inflammasome activation, cytokine production and NF-B activation or the effect of the proteins on the integrity of the epithelial barrier will be analyzed within this research module. Methods such as multicolor immunofluorescence, multiplex assays for cytokine quantification and characterization of signaling cascades, RNA sequencing or kinome analysis will be used. Theoretical part (seminar): During the research module, the pathomechanisms of chronic inflammatory skin diseases will be discussed, with a specific focus on the involvement of the immune system in the development of psoriasis vulgaris. At the same time, various possibilities how bacterial pathogens evade host immune defenses will be presented. These possibilities include the production of cell-penetrating peptides (CPEs) with anti-inflammatory properties, which can be developed as agents for therapy (drugs-from-bugs concept). Practical part: During infection, bacteria, such as Yersinia enterocolitica, can actively translocate anti-inflammatory proteins into the host cell cytoplasm to suppress the host immune response. These proteins can be produced recombinantly and are to be formulated as drugs for therapy. For this purpose, the mouse model of imiquimod-induced psoriasis-like skin inflammation was used, and the animals were treated with the bacterial compounds. After the efficacy has been proven based on the reduction in disease severity, the mechanism of action shall be analyzed in detail. For this purpose, the induction of apoptosis, the inflammasome activation, cytokine production and NF-B activation or the effect of the proteins on the integrity of the epithelial barrier will be analyzed within this research module. Methods such as multicolor immunofluorescence, multiplex assays for cytokine quantification and characterization of signaling cascades, RNA sequencing or kinome analysis will be used. Theoretical part (seminar): During the research module, the pathomechanisms of chronic inflammatory skin diseases will be discussed, with a specific focus on the involvement of the immune system in the development of psoriasis vulgaris. At the same time, various possibilities how bacterial pathogens evade host immune defenses will be presented. These possibilities include the production of cell-penetrating peptides (CPEs) with anti-inflammatory properties, which can be developed as agents for therapy (drugs-from-bugs concept).
Seminar - Dr. rer. nat. Nadine Mykicki
Prof. Dr. Karin Loser
  • Master
6.04.150.006 Perioperative Inflammation & Infection: Basic research in cardiovascular diseases - Heartfailure The course times are not decided yet.
Description:
Seminar - Dr. med. Lisa Hasselbach
Prof. Dr. Gregor Theilmeier
  • Master
6.04.131 Regenerative Medicine in Ophthalmology Dates on Thursday. 14.10.21 09:00 - 10:00, Monday. 14.02.22 - Friday. 18.02.22, Monday. 21.02.22 - Friday. 25.02.22 08:15 - 11:45
Description:
Lecture - Dr. rer. nat. Sonja Mertsch
  • Master
6.04.150.003 Immunology - Pathomechanisms and new therapeutic concepts in neuroinflammatory and neurodegenerative diseases The course times are not decided yet.
Description:
Practical part: In this module, the influence of agonists of the melanocortin-1 receptor (MC-1R) or the aryl hydrocarbon receptor (AhR) signal pathway on neuronal cells as well as immune cells will be investigated in primary cell cultures. Methodologically, mixed lymphocyte cultures, multicolor flow cytometry, various histological analyses, RNA extraction and quantitative real-time PCR will be used. The practical work will be performed mainly on primary mouse cells. Theoretical part (seminar): During the module the pathomechanisms of common CNS diseases (e.g., multiple sclerosis, Alzheimer's disease, Parkinson's disease) will be discussed in detail with a focus on the involvement of the immune system in the development as well as the progression of inflammatory and degenerative CNS diseases. At the same time, new therapeutic concepts will be discussed. Practical part: In this module, the influence of agonists of the melanocortin-1 receptor (MC-1R) or the aryl hydrocarbon receptor (AhR) signal pathway on neuronal cells as well as immune cells will be investigated in primary cell cultures. Methodologically, mixed lymphocyte cultures, multicolor flow cytometry, various histological analyses, RNA extraction and quantitative real-time PCR will be used. The practical work will be performed mainly on primary mouse cells. Theoretical part (seminar): During the module the pathomechanisms of common CNS diseases (e.g., multiple sclerosis, Alzheimer's disease, Parkinson's disease) will be discussed in detail with a focus on the involvement of the immune system in the development as well as the progression of inflammatory and degenerative CNS diseases. At the same time, new therapeutic concepts will be discussed.
Seminar - Dr. rer. nat. Nadine Mykicki
Prof. Dr. Karin Loser
  • Master
6.04.150.002 Ophthalmology – Molecular and cellular mechanisms in regenerative Medicine - Project 2 The course times are not decided yet.
Description:
Please contact the lecturer for further information. Please contact the lecturer for further information.
Seminar - Dr. rer. nat. Sonja Mertsch
  • Master
6.04.161 External Research Project 1 The course times are not decided yet.
Description:
External research projects are done on an individual basis. They are supervised by one person from Oldenburg and a local supervisor at any university or research institution in Germany and abroad. External research projects are done on an individual basis. They are supervised by one person from Oldenburg and a local supervisor at any university or research institution in Germany and abroad.
Seminar - Prof. Dr. Karl-Wilhelm Koch, Dipl.-Chem.
  • Master
6.04.193 Journal Club: Molecular Neuroscience Tuesday: 16:15 - 17:45, weekly (from 19/10/21)
Dates on Thursday. 14.10.21 10:00 - 11:00

Description:
Please select one Journal Club Please select one Journal Club
Seminar 2 Andriana Gialeli
  • Master
6.04.162 External Research Project 2 The course times are not decided yet.
Description:
External research projects are done on an individual basis. They are supervised by one person from Oldenburg and a local supervisor at any university or research institution in Germany and abroad. External research projects are done on an individual basis. They are supervised by one person from Oldenburg and a local supervisor at any university or research institution in Germany and abroad.
Seminar - Prof. Dr. Karl-Wilhelm Koch, Dipl.-Chem.
  • Master
6.04.150.005 Immunology - Environmental mimetics in neurodegenerative diseases The course times are not decided yet.
Description:
Practical part: In this module, the efficacy of environmental mimetics in a model system of multiple sclerosis will be investigated. Methodologically, a mouse model system of multiple sclerosis mixed, multicolor flow cytometry, various histological analyses, RNA extraction and quantitative real-time PCR will be used. The practical work will be performed mainly on primary mouse cells. Theoretical part (seminar): During the module the pathomechanisms of common CNS diseases (e.g., multiple sclerosis, Alzheimer's disease, Parkinson's disease) will be discussed in detail with a focus on the involvement of the immune system in the development as well as the progression of inflammatory and degenerative CNS diseases. At the same time, the relevance of environmental factors on these diseases will be discussed as well as the possibilities of environmental mimetic as therapeutic concepts. Practical part: In this module, the efficacy of environmental mimetics in a model system of multiple sclerosis will be investigated. Methodologically, a mouse model system of multiple sclerosis mixed, multicolor flow cytometry, various histological analyses, RNA extraction and quantitative real-time PCR will be used. The practical work will be performed mainly on primary mouse cells. Theoretical part (seminar): During the module the pathomechanisms of common CNS diseases (e.g., multiple sclerosis, Alzheimer's disease, Parkinson's disease) will be discussed in detail with a focus on the involvement of the immune system in the development as well as the progression of inflammatory and degenerative CNS diseases. At the same time, the relevance of environmental factors on these diseases will be discussed as well as the possibilities of environmental mimetic as therapeutic concepts.
Seminar - Dr. rer. nat. Nadine Mykicki
Prof. Dr. Karin Loser
  • Master
6.04.150.007 Perioperative Inflammation & Infection: Basic research in cardiovascular diseases - Coronary artery disease The course times are not decided yet.
Description:
Seminar - Dr. med. Lisa Hasselbach
Prof. Dr. Gregor Theilmeier
  • Master
6.04.192 Journal Club: Epigenetics Tuesday: 16:15 - 17:45, weekly (from 19/10/21)
Dates on Thursday. 14.10.21 10:00 - 11:00

Description:
Please select one Journal Club Please select one Journal Club
Seminar 2 Dr. Esther Christine Maier
  • Master
6.04.150.001 Gynaecology and Obstetrics – Immunological and cellular mechanisms of gynaecological disorders The course times are not decided yet.
Description:
Please contact Dr. Lena Dübbel for individual timing and information (during office hours or by e-mail). Please contact Dr. Lena Dübbel for individual timing and information (during office hours or by e-mail).
Seminar - Dr. Lena Dübbel
  • Master
13 Seminars

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