phy634 - Biophotonics and Spectroscopy

Attendance: 56 hrs, Self study: 124 hrs

Basics in optics and laser physics, in particular, fundamentals of optics and photonics; atomic and molecular physics; spectrophysics

The students thoroughly deepen their knowledge on concepts of spectroscopy as well as on biophotonics, This module provides the theoretical background for analytical applications involving UV-Visible spectroscopy, atomic absorption, emission and laser based spectroscopies. The students develop a sound understanding of the principles and instrumentation of atomic and molecular spectroscopy with in depth applications to a wide range of environments e.g. analytical, biological, industrial, pharmaceutical, environmental. The students develop problem solving skills with reasoning based on theory underlying spectroscopy and photonics in biosciences and medicine thus providing a background to practical laboratory training.

Application of atomic and molecular spectroscopy at a wide range of fields, e.g. industrial, biosciences, microscopy, pharmaceutical, environmental, trace analysis: 1. Explain the mechanisms of and fundamental distinctions between molecular and atomic spectroscopy 2. Recognise the issues regarding sensitivity and selectivity of molecular and atomic spectroscopy 3. Evaluate the limitations and analytical issues associated with each method 3. Demonstrate analytical application of these atomic and molecular absorption and emission techniques 4. Discriminate the analytical challenges that can be appropriately solved by these spectroscopic techniques

R. Noll: Laser-Induced Breakdown Spectroscopy. Fundamentals and Applications. Springer, Berlin, 2012. ISBN: 978-3-642-20667-2;
S. Musazzi, U. Perini (Eds.): Laser-Induced Breakdown Spectroscopy. Theory and Applications. Springer Series in Optical Sciences, Berlin, 2014. ISBN: 978-3-642-45084-6;
Braun, M., Gilch, P., Zinth, W.: Ultrashort Laser Pulses in Biology and Medicine. Springer Berlin; 2007. ISBN-13: 978-3540735656;
S. Svanberg: Atomic and molecular spectroscopy. Basic aspects and practical applications. Springer, 2004.; W. Demtröder, Laser Spectroscopy Vol. 1 and 2, Springer, 5nd ed. 2014 and 4th ed., 2008;
B. Di Bartolo, John Collins (Eds.): Biophotonics: Spectroscopy, Imaging, Sensing, and Manipulation. Springer Netherlands, 2011. ISBN: 978-90-481-9976-1;
W. Fritzsche, J. Popp (Eds.): Optical Nano- and Microsystems for Bioanalytics. Springer Series on Chemical Sensors and Biosensors, Berlin, 2012. ISBN: 978-3-642-25497-0;
Recent publications on specific topics

KL